Alcohol metabolism and why a few drinks linger longer than you think Your body processes >90% of ethanol in the liver, but the path creates toxic byproducts and drains key cofactors. 1 Acetaldehyde by DesBio Glutathione & Electrolytes: The Ultimate Hangover Cure Supplement Needs Novel physiological roles for glutathione in sequestering acetaldehyde to confer acetaldehyde tolerance in Saccharomyces cerevisiae Applied Microbiology and Biotechnology Springer Nature Link