When will the FDA reclassify BPC 157 to Category 1? Odds & Predictions Warning: BPC 157 is a synthetic peptide and an unapproved drug, often promoted with misleading claims. It is prohibited and on the DoD Prohibited Dietary Supplement Ingredients List. Don't gamble with your The Peptide Gamble: A Doctor's Warning on BPC 157 and TB 500 Some peptides are FDA approved drugs. Some are legal supplements. Some are neither. The same word, peptide, covers all three categories. The regulatory status of the specific compound is what determines legality.