Application of glutathione depletion in cancer therapy: Enhanced ROS based therapy, ferroptosis, and chemotherapy ScienceDirect Glutathione is such a critical soldier in our line of defense that our bodies make it themselves. We even have mechanisms that recycle and reuse it. But what happens when our toxic Glutathione: Master Antioxidant, Reducing Oxidative Stress, and Detoxification Current Insights into Glutathione Depletion in Adult Septic Patients