Vaping backed as healthier nicotine alternative to cigarettes after latest study The Independent The Independent What Is A Juul Pod Equivalent To In Cigarettes The great vape sham: How super strength The nicotine in 1 vape can equal 50 cigarettes. Depending on the size of the vape and nicotine strength, it can be much higher. Nicotine can harm the developing brain, affecting E cigarettes nearly twice as effective as other nicotine replacement therapies at helping smokers quit